LST: A Lesion Segmentation Tool for SPM

LST - Lesion segmentation tool The toolbox "LST: Lesion Segmentation Tool" is an open source toolbox for the segmentation of lesions in Multiple Sclerosis (MS) for SPM. It is able to detect T2 hyperintense lesions based on a T1 and a FLAIR image. Beside the segmentation a utility function for filling lesions in T1 images is implemented. Even though it is still under construction, we hope that the tool will be able to contribute to current MS research.

The toolbox was developed, see Schmidt et al. (2012), by a coorperation of the following organizations: Morphometry Group, Department of Neurology, Technische Universität München (TUM), Munich, Department of Statistics, Ludwig-Maximilians-University, Munich, Germany, and Structural Brain Mapping Group, Departments of Neurology and Psychiatry, Friedrich-Schiller-University, Jena, Germany. The reason for its development was the need for an implemented open source tool for the segmentation of lesions MS.

At this point in time, only a lesion growth algorithm is implemented, see Schmidt et al. (2012). We may include further lesion segmentation algorithms and other utility functions to this toolbox in the future.

News

2012/02/24: Version 1.1.4: File extensions are now recognized automatically. Thanks to Matthew Senjem for providing this solution.

2012/02/06: Version 1.1.3: Total lesion volume for all images can be written to a single .csv-file.

2012/02/01: Version 1.1.1 available. A bug has been fixed.

2012/01/19: Version 1.1.0 available. Beside new utility functions for the computation of binary lesion maps out of probability lesion maps and the computation of total lesion volume a more user-friendly interface for the module 'PVE-label estimation and lesion segmentation' has been set up.

2012/01/17: Version 1.0.4 available. A small bug has been fixed.

2012/01/10: Version 1.0.3 available. A small bug has been fixed.

2012/01/05: New version 1.0.2 online. Filename of segmented lesion map now includes the name of the FLAIR image.

2011/12/23: Version 1.0.1 now available. Some bugs have been fixed and this version does not depend on MATLABs Statistics Toolbox any more.

2011/12/21: Version 1.00 has been released

License

The LST toolbox is available to the scientific community under the terms of the GNU General Public License. A copy of the GNU General Public License is received along with this toolbox.

Download

To download the toolbox click on the link LST_x.x.x.zip, where x.x.x may be replaced by the newest version of the toolbox. To install the tollbox, please follow the instructions in the manual.

Lesion segmentation toolbox, version 1.1.4	6.9 MB	LST_1.1.4.zip
Manual, for version 1.1.4:	303 KB	LST_manual.pdf

Contact

Feel free to contact us: paul.schmidt@stw.de